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托法替布
发布日期: 2014-04-01
   


【英文名】tofacitinib
【商品名】XELJANZ
【适 应 症】用于治疗对甲氨蝶呤无足够应答或不能耐受的成人中度至重度活动性类风湿关节炎。
【原研公司】辉瑞
【剂型】片剂,规格5mg
【用法用量】5mg/次,每日两次。
【作用机制】Janus激酶3(JAK3)抑制剂
【国外进度】2012年11月美国FDA批准上市,2013年7月在日本上市。
【工作基础】完成中试工艺和质量研究

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